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Colchicoside & Thiocolchicoside
Colchicoside & Thiocolchicoside are the competitive GABA receptor and glycerin receptor antagonists. They are used as muscle relaxant having anti-inflammatory and analgesic effects. Thiocolchicoside is known to have chemical formula C27H33NO10S with a molar mass of 563.618 g/mol. Colchicoside & Thiocolchicoside can be administered by topical, intramuscular, or oral routes. They are known to be broken down in the form of 3-dimethylthiocolchicine and damage dividing cells.
Has biological half life of 5-6 hours
Known to have great convulsant activity
Can suppress nuclear factor kappa B ligand