Hyoscyamine Hydro Bromide

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Product Details:

Particle Size Micronized
HS Code 29420090
Molecular Formula C17H23NO3HBr
Storage Store in a cool, dry place, protected from light and moisture
Boiling point Not applicable (decomposes)
Molecular Weight 372.3 g/mol
Solubility Freely soluble in water
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Hyoscyamine Hydro Bromide Product Specifications

Smell Odorless
Appearance White to off-white crystalline powder
Structural Formula C17H23NO3HBr
CAS No 123-48-8
Loss on Drying 0.5%
Color White to off-white
Physical Form Powder
Type Active Pharmaceutical Ingredient (API)
Usage Used in treatment of gastrointestinal disorders, muscle spasms, and as an anticholinergic agent.
Grade Pharmaceutical Grade
EINECS No 204-625-7
Chemical Name Hyoscyamine Hydrobromide
Purity(%) 99%
Shelf Life 2 years
Melting Point ~145C
Particle Size Micronized
HS Code 29420090
Molecular Formula C17H23NO3HBr
Heavy Metal (%) 0.001%
Molecular Weight 372.3 g/mol
Medicine Name Hyoscyamine Hydro Bromide
Solubility Freely soluble in water
Boiling point Not applicable (decomposes)
Storage Store in a cool, dry place, protected from light and moisture
Taste Bitter
Poisonous YES
Ph Level Neutral to slightly acidic

Manufacturing Method Chemical synthesis
Residual Solvent Complies with USP/NF
Transportation Handle with care, regulated as dangerous goods
Identification IR spectrum conforms to the reference standard
Optical Rotation +20 to +24 (c=1, H2O)
Certificate of Analysis Available upon request
Microbial Limit Complies with pharmacopeial standards
Packaging Type Sealed HDPE drum or amber glass bottle
Assay (On Dried Basis) 99%
Inorganic Impurities 0.1%

Product Description

Hyoscyamine Hydro Bromide is medication which is prescribed for the treatment to provide relief from various gastrointestinal disorders. It is known to have chemical formula C17H24BrNO3 and molar mass of 370.287 g/mol. this compound is also found to be effective against symptoms of Parkinsons disease. Hyoscyamine Hydro Bromide works by inhibiting the action of acetylcholine due to its anticholinergic property. It has the ability to donate 2 and accept 4 hydrogen bonds.

Features:

Has melting point of 152 degree Celsius
It is a tropane alkaloid
Acts as an antagonist to muscarinic acetylcholine receptor

Hyoscyamine Sulfate is a tropane alkaloid that is a secondary metabolite found in certain plants of the solanaceae family. In vitro it has been shown to be an antagonist of muscarinic acetylcholine receptors.

Synonym: Levsin sulfate

Application: A tropane alkalid that is an antagonist of muscarinic acetylcholine receptors in vitro

CAS Number: 306-03-6

Molecular Weight: 676.82

Molecular Formula: C₃₄H₄₆N₂O₆H₂SO₄

Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.

Superior Chemical Purity and Standards

Hyoscyamine Hydro Bromide boasts a minimum purity of 99%, verified by both IR spectrum and dried basis assay. All manufacturing follows USP/NF and international pharmacopeial guidelines, with inorganic impurities remaining below 0.1% and heavy metals not exceeding 0.001%. This guarantees a pharmaceutical-grade product suited for high-standard medical and research applications.

Pharmaceutical Efficacy and Broad Utility

Primarily utilized in treating gastrointestinal disorders and muscle spasms, Hyoscyamine Hydro Bromide is valued for its anticholinergic effects. Its reliable performance, resulting from detailed quality controls and micronized particle size, ensures rapid and effective pharmacological response. This versatile API supports a range of therapeutic formulations globally.

Optimal Handling, Packaging, and Storage

Packed in sealed HDPE drums or amber glass bottles, Hyoscyamine Hydro Bromide is protected from moisture and light to preserve its stability. As a regulated dangerous good, it requires careful transportation and is suitable for export, import, and local supply. Proper storage extends its shelf life up to two years, maintaining quality and efficacy.

FAQs of Hyoscyamine Hydro Bromide:

Q: How is the quality and purity of Hyoscyamine Hydro Bromide assured?

A: Quality and purity are ensured by compliance with rigorous USP/NF and pharmacopeial standards. Each batch undergoes IR spectrum verification, an assay guaranteeing 99% purity, and strict limits on residual solvents, heavy metals (0.001%), and inorganic impurities (0.1%). A certificate of analysis is provided with every order upon request.

Q: What are the common uses and benefits of Hyoscyamine Hydro Bromide?

A: Hyoscyamine Hydro Bromide is widely used as an anticholinergic agent, particularly effective in treating gastrointestinal disorders, reducing muscle spasms, and other conditions requiring smooth muscle relaxation. Its rapid onset and reliable results make it a preferred component in pharmaceutical formulations.

Q: When should Hyoscyamine Hydro Bromide be stored and handled with special care?

A: It should be handled carefully at all times due to its poisonous nature and is classified as a dangerous good during transportation. Storage should always be in a cool, dry place, away from light and moisture, to ensure its stability and two-year shelf life.

Q: Where is Hyoscyamine Hydro Bromide manufactured and how is it shipped?

A: This product is manufactured in India, following stringent international standards. It is securely packed in sealed HDPE drums or amber glass bottles and transported as a regulated dangerous good, complying with global shipping and handling regulations.

Q: What methods are used in the production process of Hyoscyamine Hydro Bromide?

A: Hyoscyamine Hydro Bromide is produced through precise chemical synthesis. Following synthesis, it is processed to have fine, micronized particles and tested to confirm conformity with assay, purity, and structural specifications before packaging.

Q: How does Hyoscyamine Hydro Bromide benefit pharmaceutical manufacturers?

A: Pharmaceutical manufacturers benefit from its high purity, consistent quality, verified compliance with pharmacopeial standards, and ready availability for bulk export or local supply, ensuring optimal efficiency in creating reliable, safe therapeutic products.

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