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Quinine Base

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Quinine Base Specification

Taste
Bitter

Molecular Formula
C20H24N2O2

Poisonous
Non-poisonous at prescribed dosages

Smell
Odorless

Structural Formula
C6H4(OCH3)-(CH2)2-CH2CH(C6H4N)-C2H5(C=NH)

Molecular Weight
324.42 g/mol

Solubility
Slightly soluble in water soluble in chloroform

Particle Size
50-100 microns

Ph Level
Neutral in aqueous solution

Heavy Metal (%)
<0.001%

Melting Point
177-180°C

Color
White to off-white

Shelf Life
2 years when stored properly

Boiling point
No data available

EINECS No
204-003-9

Loss on Drying
0.5%

HS Code
29329900

Medicine Name
Quinine Base

Chemical Name
Quinine

CAS No
130-95-0

Type
Alkaloid

Grade
Pharmaceutical Grade

Usage
Used as an antimalarial drug and in tonic water production

Purity(%)
99.5%

Appearance
White to off-white crystalline powder

Physical Form
Solid

About Quinine Base

Quinine Base is a naturally derived antimalarial active pharmaceutical ingredient (API) obtained from cinchona bark. It serves as the fundamental compound for various quinine salts such as quinine sulphate, quinine hydrochloride, and quinine dihydrochloride. Known for its proven efficacy against malaria parasites, Quinine Base continues to be an essential component in the production of life-saving antimalarial medications.

Its versatility, stability, and effectiveness make it a preferred raw material for pharmaceutical manufacturers worldwide.

Key Features

High purity and controlled impurity profile

Derived from natural cinchona alkaloids

Excellent stability for long-term storage

Ideal intermediate for quinine salt production

Manufactured under strict GMP compliance

Applications

Quinine Base is widely used in:

Production of quinine-based salts and derivatives
Formulation of antimalarial medications
Treatment of malaria infections
Pharmaceutical research and development

It plays a crucial role as a base compound in multiple therapeutic formulations.

Mechanism of Action

Quinine Base works by interfering with the malaria parasites ability to digest hemoglobin inside red blood cells. This disruption leads to the accumulation of toxic substances within the parasite, ultimately causing its destruction and stopping the spread of infection.

Manufacturing Excellence

At Prism Industries Pvt. Ltd., Quinine Base is produced using advanced extraction and purification processes to ensure high quality and consistency. Our manufacturing strengths include:

GMP-compliant production facilities
Advanced purification technologies
Strict quality control systems
Scalable production capacity for bulk supply

Packaging & Storage

Packaging Options:

HDPE drums with inner liners
Customized packaging based on client needs

Storage Conditions:

Store in a cool, dry place
Protect from light and moisture
Keep containers tightly sealed

Why Choose Prism Industries Pvt. Ltd.?

Trusted API manufacturer with proven expertise
Consistent quality and reliable supply
Competitive pricing for bulk orders
Strong regulatory and documentation support
Long-term partnership approach

Conclusion:

Quinine Base remains a cornerstone API in antimalarial drug development. Its role as a primary compound for quinine derivatives makes it indispensable for pharmaceutical manufacturers. With Prism Industries Pvt. Ltd., you gain access to high-quality Quinine Base, ensuring performance, reliability, and global compliance for your formulations.

Key Advantages of Quinine Base

Quinine Base is celebrated for its effective antimalarial properties. Besides medical applications, it is also commonly used as a flavoring agent in tonic water. Its high purity and stringent pharmaceutical-grade standards ensure reliable efficacy, while neutral pH and low heavy metal content (<0.001%) enhance its safety profile for diverse applications.

Usage and Applications

Primarily utilized in pharmaceutical formulations to combat malaria, Quinine Base is also used in food and beverage industries for its distinctive bitter flavor in tonic water. This versatile alkaloid supports both health-related and commercial use-cases, underscoring its importance among suppliers, exporters, and manufacturers in India.

FAQ's of Quinine Base:

Q: What is the main use of Quinine Base?

A: Quinine Base is primarily used as an antimalarial drug in pharmaceutical preparations and as a flavoring agent in tonic water production.

Q: How should Quinine Base be stored to maximize its shelf life?

A: To ensure its 2-year shelf life, Quinine Base should be kept in a tightly sealed container away from moisture and direct sunlight, in a cool, dry location.

Q: When is it appropriate to use Quinine Base in medicinal products?

A: Quinine Base should be used for malaria treatment under medical supervision, adhering strictly to prescribed dosages to ensure efficacy and safety.

Q: Where is Quinine Base commonly sourced or manufactured?

A: Quinine Base is widely manufactured, exported, imported, and supplied by pharmaceutical companies based in India.

Q: What benefits does Quinine Base provide in its applications?

A: Quinine Base offers effective antimalarial action with high purity (99.5%) and low heavy metal content, making it suitable for both therapeutic and beverage applications.

Q: How is Quinine Base processed for pharmaceutical use?

A: Quinine Base is processed as a white to off-white crystalline powder with controlled particle sizes (50-100 microns) to ensure consistency and optimal solubility for formulation.